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2023) in resistant plants showed that glutathione was mostly deposited in the chloroplast, cytoplasm, and nucleus during PVY NTN and TuMV infections
Another clinical trial supported the usefulness of the antioxidant, N -acetylcysteine, for treating irritability in children with ASD 37
Under conditions of hypoxia, nutrient deprivation, or impaired mitochondrial function, cancer cells modulate NADPH and GSH levels through key metabolic pathways such as the pentose phosphate pathway (PPP), FAO, and glutamine metabolism, thereby establishing a metabolicredox feedback loop [39,40,41]